{"id":10994,"date":"2022-12-16T10:26:30","date_gmt":"2022-12-16T09:26:30","guid":{"rendered":"https:\/\/fei-online.com\/?p=10994"},"modified":"2022-12-16T10:31:30","modified_gmt":"2022-12-16T09:31:30","slug":"nutri-tech-start-up-novella-leverages-advanced-technology-to-grow-botanical-ingredients-in-the-lab","status":"publish","type":"post","link":"https:\/\/fei-online.com\/nutri-tech-start-up-novella-leverages-advanced-technology-to-grow-botanical-ingredients-in-the-lab\/","title":{"rendered":"Nutri-tech start-up Novella leverages advanced technology to grow botanical ingredients in the lab"},"content":{"rendered":"<div id='av_section_1'  class='avia-section main_color avia-section-default avia-no-border-styling  avia-bg-style-scroll  avia-builder-el-0  avia-builder-el-no-sibling   container_wrap fullsize' style=' '  ><div class='container' ><main  role=\"main\" itemprop=\"mainContentOfPage\"  class='template-page content  av-content-full alpha units'><div class='post-entry post-entry-type-page post-entry-10994'><div class='entry-content-wrapper clearfix'>\n<div class=\"flex_column av_one_fifth  flex_column_div av-zero-column-padding first  avia-builder-el-1  el_before_av_three_fifth  avia-builder-el-first  \" style='border-radius:0px; '><section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock  '   itemprop=\"text\" ><p style=\"text-align: center\"><div id=\"ads-slider-28\" class=\"custom-slider ads-slider-1757197839 ads-slider\"><ul><li><!--Begin ClixTrac.com Banner Code -->\r\n<a href=\"https:\/\/clixtrac.com\/goto\/?308404\" target=\"_blank\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/clixtrac.com\/banner\/308404.jpg\" alt=\"Free from food\" title=\"Free from food\" border=\"0\" \/><\/a>\r\n<!--End ClixTrac.com Banner Code --><\/li><li><!--Begin ClixTrac.com Banner Code -->\r\n<a href=\"https:\/\/clixtrac.com\/banner\/click.php?banner=302805\" target=\"_blank\" rel=\"noopener\">\r\n<img decoding=\"async\" src=\"https:\/\/clixtrac.com\/banner\/302805.jpg\" alt=\"LUBRIPLATE\" title=\"LUBRIPLATE\" border=\"0\" width=\"120\" height=\"600\" \/><\/a>\r\n<!--End ClixTrac.com Banner Code --><\/li><li><div style=\"margin-left: auto; margin-right: auto; text-align: center; \" id=\"ads-1571380554\"><!--Begin ClixTrac.com Banner Code -->\r\n<a href=\"https:\/\/clixtrac.com\/banner\/click.php?banner=297426\" target=\"_blank\" rel=\"noopener\">\r\n<img decoding=\"async\" width=\"100%\" height=\"auto\" src=\"https:\/\/clixtrac.com\/banner\/297426.jpg\" alt=\"Click here for more information!\" title=\"Click here for more information!\" border=\"0\" \/><\/a>\r\n<!--End ClixTrac.com Banner Code --><\/div><\/li><\/ul><\/div><script>( window.advanced_ads_ready || jQuery( document ).ready ).call( null, function() {var $adsslider1757197839 = jQuery( \".ads-slider-1757197839\" );$adsslider1757197839.on( \"unslider.ready\", function() { jQuery( \"div.custom-slider ul li\" ).css( \"display\", \"block\" ); });$adsslider1757197839.unslider({ delay:5000, autoplay:true, nav:false, arrows:false, infinite:true });$adsslider1757197839.on(\"mouseover\", function(){$adsslider1757197839.unslider(\"stop\");}).on(\"mouseout\", function() {$adsslider1757197839.unslider(\"start\");});});<\/script><\/p>\n<\/div><\/section><\/div><div class=\"flex_column av_three_fifth  flex_column_div av-zero-column-padding   avia-builder-el-3  el_after_av_one_fifth  el_before_av_one_fifth  \" style='border-radius:0px; '><section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock  '   itemprop=\"text\" ><p style=\"text-align: center\"><\/p>\n<\/div><\/section><br \/>\n<section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock  '   itemprop=\"text\" ><header class=\"entry-content-header\"><h1 class=\"post-title entry-title\" itemprop=\"headline\">Nutri-tech start-up Novella leverages advanced technology to grow botanical ingredients in the lab<\/h1><span class=\"post-meta-infos\">\/ <span class=\"blog-categories minor-meta\">in <a href=\"https:\/\/fei-online.com\/category\/e-news\/\" rel=\"tag\">E-News<\/a> <\/span><\/span><\/header>\n<\/div><\/section><br \/>\n<section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock  '   itemprop=\"text\" ><h3>Nutri-tech start-up Novella is opening a new chapter in climate-resilient environments through nutrient cultivation. The company leveraged proprietary technology to grow nutritious botanical ingredients while leaving the whole plant out of the equation. This novel platform will help boost global accessibility to high-value nutraceuticals.<\/h3>\n<p><!--more--><\/p>\n<p>Addressing the growing demand for botanical micronutrients, the new technology overcomes supply chain disruptions, circumvents climate change, and expands plant life cycles.<\/p>\n<\/div><\/section><br \/>\n<div  class='avia-image-container  av-styling-    avia-builder-el-7  el_after_av_textblock  el_before_av_textblock  avia-align-center '  itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\"  ><div class='avia-image-container-inner'><div class='avia-image-overlay-wrap'><img class='avia_image' src='https:\/\/fei-online.com\/wp-content\/uploads\/sites\/4\/2022\/12\/Novella-team-2022.jpg' alt='' title='Novella team 2022' height=\"756\" width=\"1008\"  itemprop=\"thumbnailUrl\"  \/><\/div><\/div><\/div><br \/>\n<section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock  '   itemprop=\"text\" ><p><em>The team at Novella, a nutri-tech start-up developing climateresilient nutrient cultivation.<\/em><\/p>\n<\/div><\/section><br \/>\n<div   class='hr hr-default   avia-builder-el-9  el_after_av_textblock  el_before_av_textblock '><span class='hr-inner ' ><span class='hr-inner-style'><\/span><\/span><\/div><br \/>\n<section class=\"av_textblock_section \"  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/BlogPosting\" itemprop=\"blogPost\" ><div class='avia_textblock  '   itemprop=\"text\" ><p>We don\u2019t need the whole plant to get access to specific bioactive compounds,\u201d explained Kobi Avidan, CEO and co-founder of Novella. \u201cIt also isn\u2019t necessary to discard up to 99% of a plant and incur tons of agricultural waste just to derive specific nutrients. We have the technology where we can narrow the harvest of an entire field for its plant essence in a single bioreactor.\u201d<\/p>\n<p>The traditional \u201cfield to bottle\u201d protocol for producing nutraceuticals involves a long, complex, and often vexing process of lengthy cultivation and labour-intensive harvesting of sensitive botanicals, and the use of vast stretches of agricultural land. Then, the raw materials must be transferred \u2013 often overseas \u2013 to a factory for extraction before transfer to another factory, often in yet another country, for formulation into a final supplement. This can also lead to difficulties in achieving standardized doses of the natural substances.<\/p>\n<p>The supply chain for botanical extracts is continuously at the mercy of the natural growth cycles of the plants, volatile environmental conditions, climate fluctuations, and social and economic constraints. These have been further compounded by recent political instabilities and logistical hurdles which have yet to recover from the pandemic era.<\/p>\n<p>All of these setbacks hit the nutraceutical business at a time when it is experiencing its greatest boom ever, attaining a global value of billions of US dollars. This has put further immense strain on industry to meet demand, as well as on the planet\u2019s finite resources.<\/p>\n<p>Rather than grow the whole plant, Novella screens specific plant tissues \u2013 including stems, fruit, leaves, and flowers \u2013 to determine the highest concentrations of desired actives. A cell culture (callus) is formed from these tissues and amplified in bioreactors. This results in a pure, pesticide-free powdered product composed of whole-cell plant tissues with their naturally occurring complex of nutrients intact.<\/p>\n<p>Novella\u2019s cultivation system eliminates the need for extraction by increasing the concentration of the actives within the plant cells themselves, which are contained in a natural protective shell to prevent oxidation. This also assures full bioavailability.<\/p>\n<p>\u201cGrowing nutrients outside the plant is actually a simpler process than growing meat cells outside of the cow,\u201d explained Avidan. \u201cMore-over, we can now cultivate any ingredient close to the market of interest. This will be instrumental in lowering costs, as well as lightening their ecological footprint.\u201d<br \/>\nThe start-up will grow the ingredients in a controlled, strictly non-GMO environment, with precise regulation of stressors such as light and temperature in order to create an ideal environment for cultivation of specific bioactives at consistently potent and highly precise quantities.<\/p>\n<p>Novella has made headway in exploring certain vegetables, such as kale, for sourcing some popular in demand vitamins and antioxidants. Although hailed as a nutrient-dense \u201csuper plant\u201d, many consumers avoid kale due to its bitter flavour and tough, fibrous texture.<\/p>\n<p>\u201cKale has captured the interest of the functional food, supplement, and pharma industries due to its long list of vitamins and minerals,\u201d said Shimrit Bar-El, PhD, co-founder and CRO of Novella. \u201cBut it is very difficult to work with and process. We are specifically exploring the vegetable for its vitamin K and unique carotenoid composition.\u201d<\/p>\n<p>Novella can grow any type of plant tissue but currently is focusing on the cultivation of a few high-end botanicals, including some widely consumed vegetables that boast potent concentrations of nutrients such as vitamin C that cannot be extracted via existing methods.<\/p>\n<p>\u201cBy shifting the cultivation of popular micronutrients to the lab, the Novella platform can help free up extensive agricultural terrain for rededication to the growth of food crops while making high-value nutraceutical ingredients more readily available at affordable prices,\u201d explained Itay Dana, B.Sc., MBA, co-founder and BDO for Novella.<\/p>\n<\/div><\/section><br \/>\n<div  class='av-social-sharing-box  avia-builder-el-11  el_after_av_textblock  avia-builder-el-last  av-social-sharing-box-minimal '><div class='av-share-box'><h5 class='av-share-link-description av-no-toc '>Share this<\/h5><ul class='av-share-box-list noLightbox'><li class='av-share-link av-social-link-facebook' ><a target=\"_blank\" aria-label=\"Share on Facebook\" href='https:\/\/www.facebook.com\/sharer.php?u=https:\/\/fei-online.com\/nutri-tech-start-up-novella-leverages-advanced-technology-to-grow-botanical-ingredients-in-the-lab\/&#038;t=Nutri-tech%20start-up%20Novella%20leverages%20advanced%20technology%20to%20grow%20botanical%20ingredients%20in%20the%20lab' aria-hidden='false' data-av_icon='\ue8f3' data-av_iconfont='entypo-fontello' title='' data-avia-related-tooltip='Share on Facebook' rel=\"noopener\"><span class='avia_hidden_link_text'>Share on Facebook<\/span><\/a><\/li><li class='av-share-link av-social-link-twitter' ><a target=\"_blank\" aria-label=\"Share on Twitter\" href='https:\/\/twitter.com\/share?text=Nutri-tech%20start-up%20Novella%20leverages%20advanced%20technology%20to%20grow%20botanical%20ingredients%20in%20the%20lab&#038;url=https:\/\/fei-online.com\/?p=10994' aria-hidden='false' data-av_icon='\ue8f1' data-av_iconfont='entypo-fontello' title='' data-avia-related-tooltip='Share on Twitter' rel=\"noopener\"><span class='avia_hidden_link_text'>Share on Twitter<\/span><\/a><\/li><li class='av-share-link av-social-link-whatsapp' ><a target=\"_blank\" aria-label=\"Share on WhatsApp\" href='https:\/\/api.whatsapp.com\/send?text=https:\/\/fei-online.com\/nutri-tech-start-up-novella-leverages-advanced-technology-to-grow-botanical-ingredients-in-the-lab\/' aria-hidden='false' data-av_icon='\uf232' data-av_iconfont='entypo-fontello' title='' data-avia-related-tooltip='Share on WhatsApp' rel=\"noopener\"><span class='avia_hidden_link_text'>Share on WhatsApp<\/span><\/a><\/li><li class='av-share-link av-social-link-linkedin' ><a target=\"_blank\" aria-label=\"Share on LinkedIn\" href='https:\/\/linkedin.com\/shareArticle?mini=true&#038;title=Nutri-tech%20start-up%20Novella%20leverages%20advanced%20technology%20to%20grow%20botanical%20ingredients%20in%20the%20lab&#038;url=https:\/\/fei-online.com\/nutri-tech-start-up-novella-leverages-advanced-technology-to-grow-botanical-ingredients-in-the-lab\/' aria-hidden='false' data-av_icon='\ue8fc' data-av_iconfont='entypo-fontello' title='' data-avia-related-tooltip='Share on LinkedIn' rel=\"noopener\"><span class='avia_hidden_link_text'>Share on LinkedIn<\/span><\/a><\/li><li class='av-share-link av-social-link-mail' ><a  aria-label=\"Share by Mail\" href='mailto:?subject=Nutri-tech%20start-up%20Novella%20leverages%20advanced%20technology%20to%20grow%20botanical%20ingredients%20in%20the%20lab&#038;body=https:\/\/fei-online.com\/nutri-tech-start-up-novella-leverages-advanced-technology-to-grow-botanical-ingredients-in-the-lab\/' aria-hidden='false' data-av_icon='\ue805' data-av_iconfont='entypo-fontello' title='' data-avia-related-tooltip='Share by Mail'><span class='avia_hidden_link_text'>Share by Mail<\/span><\/a><\/li><\/ul><\/div><\/div><\/p><\/div><div class=\"flex_column av_one_fifth  flex_column_div av-zero-column-padding   avia-builder-el-12  el_after_av_three_fifth  avia-builder-el-last  \" style='border-radius:0px; 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The company leveraged proprietary technology to grow nutritious botanical ingredients while leaving the whole plant out of the equation. This novel platform will help boost global accessibility to high-value nutraceuticals.<\/p>\n","protected":false},"author":3,"featured_media":10946,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[3],"tags":[],"_links":{"self":[{"href":"https:\/\/fei-online.com\/wp-json\/wp\/v2\/posts\/10994"}],"collection":[{"href":"https:\/\/fei-online.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/fei-online.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/fei-online.com\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/fei-online.com\/wp-json\/wp\/v2\/comments?post=10994"}],"version-history":[{"count":3,"href":"https:\/\/fei-online.com\/wp-json\/wp\/v2\/posts\/10994\/revisions"}],"predecessor-version":[{"id":11003,"href":"https:\/\/fei-online.com\/wp-json\/wp\/v2\/posts\/10994\/revisions\/11003"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/fei-online.com\/wp-json\/wp\/v2\/media\/10946"}],"wp:attachment":[{"href":"https:\/\/fei-online.com\/wp-json\/wp\/v2\/media?parent=10994"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/fei-online.com\/wp-json\/wp\/v2\/categories?post=10994"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/fei-online.com\/wp-json\/wp\/v2\/tags?post=10994"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}