DolCas Biotech infuses chocolate with 1g fish collagen tripeptides
DolCas Biotech has successfully demonstrated the incorporation of marine collagen tripeptides into chocolate confections, achieving clinically effective dosing in an 8g serving whilst maintaining organoleptic properties. The New Jersey-based nutraceutical company utilises its proprietary Morikol ingredient to deliver 1g of ultra-low molecular weight fish collagen per chocolate square.
The development represents a significant advancement in functional food applications for marine-derived bioactive peptides. Traditional collagen supplementation typically requires 5-10g doses, presenting formulation challenges for confectionery applications due to bulk density and potential sensory impacts.
Low molecular weight enables chocolate integration
Morikol comprises Type I and III fish collagen tripeptides with exceptionally low molecular weight, facilitating high bioavailability and rapid absorption. The ingredient contains functional glycine-proline-hydroxyproline (GPH) tripeptide sequences that have demonstrated stimulation of collagen generation and synthesis of hyaluronic acid and ceramide enzymes.
“Most collagen ingredients come in 5g-10g doses,” explains K. G. Rao, founder and CEO of DolCas Biotech. “Morikol’s low concentration of the bioactive component makes it ideal for innovative delivery formats. One square of chocolate can now deliver a full clinical dose of collagen peptides, whether for beauty-from-within or joint comfort, and still satisfy the most discerning chocolate lover’s palate.”
The concentrated powder demonstrates odourless, neutral flavour characteristics with high solubility, enabling integration into milk, dark, or white chocolate matrices without affecting flavour, aroma, or texture parameters.
Clinical validation at minimal doses
Clinical research supports Morikol’s efficacy at uniquely low dosing levels. A 12-week randomised controlled trial involving 53 female volunteers demonstrated significant improvements in skin elasticity and dermal hydration following daily 1g intake. The treatment group exhibited 10.5-fold greater improvement in wrinkle visual scores compared to placebo at 12 weeks, with benefits observable from six weeks, particularly around cheek and periorbital regions.
“This is the only fish collagen clinically studied to deliver measurable benefits for skin health at a daily 1g dose, or for joint mobility at a 2g daily dose,” affirms Rao.
A separate 10-week study with 64 participants experiencing mild knee discomfort found that 2g daily Morikol intake reduced periarticular fluid accumulation whilst mitigating joint crepitus and pain symptoms.
Bioavailability mechanisms
Preclinical studies have elucidated Morikol’s absorption pathway, demonstrating intact tripeptide uptake across intestinal barriers via PEPT1 transporters. This mechanism results from the ingredient’s specific hydrolysed enzyme formulation. Cell culture studies show increased mRNA expression for collagen production following tripeptide exposure.
“Morikol’s piscine tripeptides are designed to reach vulnerable and damaged sites of the skin, bone, and tendons where it activates osteoblasts and fibroblasts, in turn helping promote collagen synthesis, boosting bone and connective tissue integrity as well as keeping joints lubricated,” Rao elaborates.
Clean label attributes
The ingredient maintains non-GMO status with sustainable sourcing protocols. Quality specifications include testing for dioxins, PCBs, hormones, and synthetic compounds. Kosher and halal certifications support broad market applications.
“Morikol is non-GMO, sustainable, allergen-friendly, and is completely free of any fishy aroma or flavour, making it a perfect candidate for expansion into functional foods,” adds Rao. “Our full spectrum, clean-label collagen offers a turn-key opportunity to elevate chocolate products into the wellness arena, without compromising on their classic treats’ flavour and the enjoyment of snacking.”
