Danish biotech company Biosyntia and the Munich-based WACKER Group will form a partnership to develop a large-scale production process for fermentation-based biotin. The aim of the collaboration is to make fermentation-based biotin available for the market as a sustainable, non-chemical, European-sourced alternative. The biotin currently available on the market is synthetically produced from non-renewable petrochemicals.
Biotin, also known as vitamin B7, is a coenzyme for the metabolism of proteins, fats and carbohydrates. The European Food Safety Authority (EFSA) attributes health-promoting effects to biotin, including, for example, that it contributes to normal functioning of the nervous system and macronutrient metabolisms as well as to the maintenance of normal skin and hair.
Demand for biotin, which is also used as a dietary supplement, is rising sharply – driven by the health and well-being trend. A recent study predicts growth of around 10 percent per year in the coming years. In 2026, the global biotin market is expected to reach a volume of US$376 million.
Sustainable fermentation, the future of production
WACKER and Biosyntia will jointly develop a large-scale biotin production process based on sustainable fermentation. The companies are dedicating considerable R&D resources in a multi-year program, which will build on Biosyntia’s world-leading biotin technology. Only plant-based raw materials will be used in the fermentative production.
“Demand for more natural products is increasing – and with it the need for companies to use ingredients that are sustainable. Producing active ingredients from advanced fermentation is the future of production,” explained Martin Plambech, CEO of Biosyntia.
Biotin has a wide range of applications in food & beverages, infant nutrition, nutraceuticals, pet food, animal feed, pharmaceuticals and cosmetics.
“With fermentation-based biotin, we want to offer customers a non-chemical, sustainable alternative that is produced in Europe,” said Susanne Leonhartsberger, President of WACKER Biosolutions, WACKER’s life science division.
Biosyntia is considered a global leader in the development of fermentation processes for production of selected small molecules. The Danish biotech company has a proprietary microbial technology platform, on which it is building a rapidly growing pipeline of active ingredients for the beauty and nutrition industries. WACKER brings strong expertise in biotechnological process development and industrial-scale fermentation to the partnership. The company also has a deep understanding of requirements and regulations of the food and nutraceutical industry. WACKER offers a broad portfolio here, including fermentation-based L-cysteine and solutions for formulating effective dietary supplements.